Path of Destruction (滅びの道, Horobi no Michi) is the twenty-first episode of Mobile Suit Gundam 00.

The United Nations forces have deployed their new weapon, a mobile suit model known as the GN-X which is powered by a pseudo solar reactor. While Sergei Smirnov and Soma Peries lead a GN-X team in pursuit of the Gundam Thrones, another force attacks the Ptolemaios in space. Orchestrating all this is Alejandro Corner, the rogue Observer who has betrayed Celestial Being. Having provided the United Nations with its powerful new weapons, Alejandro now enters the very core of the supercomputer Veda.

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